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In studies on human skin, prolonged delivery time is shown to cause significant reduction of radiation effects compared with acute irradiation. In this paper the effect of changes in fraction delivery time was studied by in vitro irradiation of mammalian cells.

13 thg 3, 2015 · Our results showed that fractionated irradiation with prolonged FDTs (15, 36 and 50 minutes) enhanced cell surviving fractions for normal tissue cells compared with irradiation with an...

In this study, an in-vitro experiment using human cell line ACHN was performed to examine the effect of prolonged fraction delivery time in SBRT on cell killing, with a total high dose of 18 Gy in 1, 2 or 3 fractions with six equal sub-fractions per fraction.

Survival curves manually plotted based on surviving fractions of cell lines (a) CNE1 and (b) CNE2 after fractionated irradiation with 2 Gy per fraction simulating conventional external beam radiotherapy (EBRT) (plus signs) and intensity-modulated radiotherapy (IMRT) with a fraction time of 15 minutes (times signs), 36 minutes (squares), or 50 ...

1 thg 12, 2010 · In this study we chose these two cell lines to determine the impact of prolonged FDTs simulating IMRT on NPC cell killing. Human NPC cell lines including CNE1 and CNE2 were used in this study.

In this study, our results indicated that although prolonged FDTs simulating HPR increased cell surviving fractions for both acute-responding and late-responding normal tissue cell lines, late-responding normal tissue cell lines obtained greater benefit from prolonged FDTs.

1 thg 12, 2010 · To determine the impact of prolonged fraction delivery times (FDTs) simulating intensity-modulated radiotherapy (IMRT) on cultured nasopharyngeal carcinoma (NPC) cell killing. Cultured NPC cell lines CNE1 and CNE2 were used in this study.

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